:root {
  color-scheme: light;
  --bg: #f4f7f9;
  --surface: #ffffff;
  --text: #14232f;
  --muted: #5c6f80;
  --border: #d5dee6;
  --primary: #0b6e7a;
  --primary-hover: #095b66;
  --danger: #b42318;
  --radius: 10px;
  --shadow: 0 8px 28px rgba(20, 35, 47, 0.08);
  font-family: "DM Sans", system-ui, sans-serif;
  line-height: 1.45;
  color: var(--text);
  background: var(--bg);
}

*,
*::before,
*::after {
  box-sizing: border-box;
}

body {
  margin: 0;
  min-height: 100vh;
}

.mono {
  font-family: "JetBrains Mono", ui-monospace, monospace;
}

a {
  color: var(--primary);
}

.app-shell {
  min-height: 100vh;
  display: flex;
  flex-direction: column;
}

.app-header {
  background:
    radial-gradient(1200px 300px at 90% -10%, rgba(122, 213, 235, 0.22), transparent 60%),
    radial-gradient(800px 240px at -10% 110%, rgba(33, 127, 167, 0.2), transparent 55%),
    linear-gradient(135deg, #072f38 0%, #0b5b69 48%, #15808f 100%);
  color: #f4fbfc;
  padding: 1.1rem 1.5rem 1.4rem;
  box-shadow: var(--shadow);
}

.header-shell {
  max-width: 1200px;
  margin: 0 auto;
  border: 1px solid rgba(255, 255, 255, 0.15);
  background: rgba(255, 255, 255, 0.07);
  backdrop-filter: blur(6px);
  border-radius: 14px;
  padding: 0.95rem 1rem 0.85rem;
}

.header-brand {
  display: grid;
  grid-template-columns: minmax(92px, 140px) 1fr minmax(92px, 140px);
  align-items: center;
  gap: 1.1rem;
}

.header-logo-left,
.header-logo-right {
  display: flex;
  align-items: center;
}

.header-logo-left {
  justify-content: flex-start;
}

.header-logo-right {
  justify-content: flex-end;
}

.header-titles {
  text-align: center;
}

.logo {
  max-height: 78px;
  width: auto;
  object-fit: contain;
  background: rgba(255, 255, 255, 0.95);
  padding: 7px 10px;
  border-radius: 10px;
  box-shadow: 0 6px 20px rgba(0, 0, 0, 0.18);
}

.logo-secondary {
  max-height: 74px;
}

.header-titles .eyebrow {
  display: block;
  font-size: 0.71rem;
  text-transform: uppercase;
  letter-spacing: 0.13em;
  opacity: 0.9;
  margin-bottom: 0.2rem;
}

.header-titles .title {
  margin: 0 0 0.15rem;
  font-size: clamp(1.2rem, 1.2rem + 0.6vw, 1.65rem);
  font-weight: 700;
}

.header-subtitle {
  margin: 0;
  opacity: 0.92;
  font-size: 0.92rem;
}

.header-tags {
  display: flex;
  flex-wrap: wrap;
  justify-content: center;
  gap: 0.4rem;
  margin-top: 0.55rem;
}

.header-tag {
  display: inline-flex;
  align-items: center;
  border: 1px solid rgba(255, 255, 255, 0.25);
  padding: 0.2rem 0.52rem;
  border-radius: 999px;
  font-size: 0.72rem;
  font-weight: 600;
  letter-spacing: 0.04em;
  background: rgba(255, 255, 255, 0.1);
}

.main-nav {
  display: flex;
  flex-wrap: wrap;
  gap: 0.45rem;
  margin-top: 0.95rem;
  padding-top: 0.8rem;
  border-top: 1px solid rgba(255, 255, 255, 0.22);
}

.nav-link {
  color: #f3fbfd;
  text-decoration: none;
  padding: 0.48rem 0.9rem;
  border-radius: 999px;
  font-weight: 600;
  font-size: 0.88rem;
  opacity: 0.92;
  border: 1px solid rgba(255, 255, 255, 0.16);
  background: rgba(255, 255, 255, 0.06);
  transition: all 120ms ease;
}

.nav-link-button {
  font: inherit;
  cursor: pointer;
}

.nav-link:hover {
  background: rgba(255, 255, 255, 0.16);
  border-color: rgba(255, 255, 255, 0.32);
  opacity: 1;
}

.nav-link-active {
  color: #083741;
  background: linear-gradient(135deg, #dbf5fb 0%, #bdeefa 100%);
  border-color: rgba(255, 255, 255, 0.6);
  opacity: 1;
}

@media (max-width: 760px) {
  .header-brand {
    grid-template-columns: 1fr;
    gap: 0.75rem;
  }

  .header-logo-left,
  .header-logo-right {
    justify-content: center;
  }

  .header-shell {
    padding: 0.85rem;
  }

  .logo {
    max-height: 62px;
  }

  .logo-secondary {
    max-height: 58px;
  }
}

.main-content {
  flex: 1;
  padding: 1.5rem clamp(1rem, 4vw, 2.5rem) 3rem;
  max-width: 1200px;
  width: 100%;
  margin: 0 auto;
}

.app-footer {
  padding: 1rem 1.5rem;
  font-size: 0.8rem;
  color: var(--muted);
  border-top: 1px solid var(--border);
  background: var(--surface);
}

.alert {
  margin: 0 auto;
  max-width: 1200px;
  padding: 0.65rem 1.25rem;
  display: flex;
  justify-content: space-between;
  align-items: center;
  gap: 1rem;
}

.alert-error {
  background: #fde8e6;
  color: #691810;
  border-bottom: 1px solid #f4bbb4;
}

.alert-success {
  background: #e6f6ec;
  color: #14532d;
  border-bottom: 1px solid #b7e4c7;
}

.form-grid-2 {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 1rem;
}

@media (max-width: 560px) {
  .form-grid-2 {
    grid-template-columns: 1fr;
  }
}

.req {
  color: #c0392b;
  margin-left: 2px;
}

.page-head h2 {
  margin: 0 0 0.35rem;
}

.page-head.split {
  display: flex;
  flex-wrap: wrap;
  justify-content: space-between;
  gap: 1rem;
  align-items: flex-start;
}

.muted {
  color: var(--muted);
}

.small {
  font-size: 0.85rem;
}

.card {
  background: var(--surface);
  border: 1px solid var(--border);
  border-radius: var(--radius);
  padding: 1.25rem 1.35rem;
  margin-bottom: 1.25rem;
  box-shadow: var(--shadow);
}

.hero.card h2 {
  margin-top: 0;
}

.status-pill {
  display: inline-block;
  margin-top: 0.75rem;
  padding: 0.35rem 0.75rem;
  border-radius: 999px;
  font-size: 0.85rem;
  font-weight: 600;
}

.status-pill.ok {
  background: #e6f5ec;
  color: #12522a;
}

.status-pill.bad {
  background: #fde8e6;
  color: #691810;
}

.stat-grid {
  display: grid;
  grid-template-columns: repeat(auto-fill, minmax(160px, 1fr));
  gap: 1rem;
  margin-bottom: 1.25rem;
}

.stat {
  text-align: center;
}

.stat-value {
  display: block;
  font-size: 1.85rem;
  font-weight: 700;
  color: var(--primary);
}

.stat-label {
  font-size: 0.85rem;
  color: var(--muted);
}

.gene-list {
  list-style: none;
  padding: 0;
  margin: 0;
  display: grid;
  gap: 0.35rem;
}

.gene-list li {
  display: flex;
  justify-content: space-between;
  padding: 0.35rem 0;
  border-bottom: 1px solid var(--border);
}

.workflow ol {
  padding-left: 1.15rem;
}

.workflow li {
  margin-bottom: 0.35rem;
}

.actions-row {
  display: flex;
  flex-wrap: wrap;
  gap: 0.5rem;
  margin-top: 0.75rem;
}

.btn {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  padding: 0.45rem 1rem;
  border-radius: 8px;
  border: 1px solid var(--border);
  background: var(--surface);
  color: var(--text);
  font: inherit;
  font-weight: 500;
  cursor: pointer;
  text-decoration: none;
}

.btn:hover {
  border-color: #aab9c6;
}

.btn.primary {
  background: var(--primary);
  border-color: var(--primary);
  color: #fff;
}

.btn.primary:hover {
  background: var(--primary-hover);
  border-color: var(--primary-hover);
}

.btn.small {
  padding: 0.25rem 0.55rem;
  font-size: 0.82rem;
}

.btn.danger {
  border-color: #e8a29e;
  color: var(--danger);
}

.btn.danger:hover {
  background: #fde8e6;
}

.btn-text {
  background: none;
  border: none;
  cursor: pointer;
  font: inherit;
  color: var(--primary);
  padding: 0;
}

.btn-text.danger {
  color: var(--danger);
}

.stack-form {
  display: flex;
  flex-direction: column;
  gap: 0.85rem;
}

.stack-form label {
  display: flex;
  flex-direction: column;
  gap: 0.35rem;
  font-weight: 500;
  font-size: 0.88rem;
}

input,
textarea,
select {
  font: inherit;
  padding: 0.45rem 0.55rem;
  border-radius: 8px;
  border: 1px solid var(--border);
  background: #fff;
}

textarea {
  resize: vertical;
}

.table-wrap {
  overflow-x: auto;
}

.data-table {
  width: 100%;
  border-collapse: collapse;
  font-size: 0.88rem;
}

.data-table th,
.data-table td {
  text-align: left;
  padding: 0.55rem 0.6rem;
  border-bottom: 1px solid var(--border);
  vertical-align: top;
}

.data-table th {
  font-size: 0.72rem;
  text-transform: uppercase;
  letter-spacing: 0.06em;
  color: var(--muted);
}

.actions-cell {
  white-space: nowrap;
}

.actions-cell .btn {
  margin-right: 0.35rem;
}

.clamp {
  max-width: 280px;
  overflow: hidden;
  text-overflow: ellipsis;
}

.filter-bar {
  display: flex;
  flex-wrap: wrap;
  gap: 0.75rem;
  align-items: flex-end;
}

.filter-bar label {
  display: flex;
  flex-direction: column;
  gap: 0.25rem;
  font-size: 0.8rem;
  font-weight: 600;
}

.pager {
  display: flex;
  align-items: center;
  gap: 1rem;
  margin-top: 1rem;
}

.back-link {
  text-decoration: none;
  font-weight: 600;
  font-size: 0.9rem;
}

.dl-grid {
  display: grid;
  grid-template-columns: repeat(auto-fill, minmax(220px, 1fr));
  gap: 0.35rem 1rem;
}

.dl-grid.dense {
  font-size: 0.85rem;
}

.dl-row dt {
  margin: 0;
  color: var(--muted);
  font-size: 0.78rem;
}

.dl-row dd {
  margin: 0 0 0.45rem;
}

.pill-list {
  list-style: none;
  padding: 0;
  margin: 0 0 0.75rem;
}

.pill {
  display: inline-flex;
  align-items: center;
  gap: 0.5rem;
  padding: 0.35rem 0.65rem;
  border-radius: 999px;
  background: #eef5f7;
  margin: 0 0.35rem 0.35rem 0;
  font-size: 0.88rem;
}

.inline-form {
  display: flex;
  flex-wrap: wrap;
  gap: 0.5rem;
  align-items: center;
}

/* ── Variant detail ── */
.variant-detail {
  display: flex;
  flex-direction: column;
  gap: 1rem;
}

.variant-hero {
  display: flex;
  flex-direction: column;
  gap: 0.75rem;
}

.variant-hero-main {
  display: flex;
  flex-wrap: wrap;
  justify-content: space-between;
  align-items: flex-start;
  gap: 1rem;
}

.variant-coords {
  margin: 0.25rem 0 0.4rem;
  font-size: 1.5rem;
}

.variant-hero-sub {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  gap: 0.5rem 0.75rem;
  margin: 0;
}

.gene-chip {
  background: #0b5394;
  color: #fff;
  font-weight: 700;
  padding: 0.15rem 0.6rem;
  border-radius: 6px;
  font-size: 0.9rem;
}

.vbadge-row {
  display: flex;
  flex-wrap: wrap;
  gap: 0.5rem;
}

.vbadge {
  display: inline-flex;
  align-items: stretch;
  border-radius: 7px;
  overflow: hidden;
  font-size: 0.82rem;
  border: 1px solid transparent;
}

.vbadge-label {
  background: rgba(0, 0, 0, 0.06);
  padding: 0.28rem 0.55rem;
  font-weight: 600;
  color: #333;
}

.vbadge-value {
  padding: 0.28rem 0.6rem;
  font-weight: 600;
}

.vbadge-path { background: #fde8e6; border-color: #f4bbb4; }
.vbadge-path .vbadge-value { color: #8b1a0f; }
.vbadge-benign { background: #e6f6ec; border-color: #b7e4c7; }
.vbadge-benign .vbadge-value { color: #14532d; }
.vbadge-vus { background: #fff4e0; border-color: #f3d9a6; }
.vbadge-vus .vbadge-value { color: #8a5b00; }
.vbadge-neutral { background: #eef2f5; border-color: #d7dee4; }
.vbadge-neutral .vbadge-value { color: #334; }

.variant-form details {
  margin-bottom: 1rem;
}

.variant-form summary {
  cursor: pointer;
  font-weight: 600;
  margin-bottom: 0.65rem;
}

.field-grid {
  display: grid;
  grid-template-columns: repeat(auto-fill, minmax(200px, 1fr));
  gap: 0.65rem;
}

.field-grid .full-width {
  grid-column: 1 / -1;
}

.field-row {
  display: flex;
  flex-direction: column;
  gap: 0.35rem;
  font-size: 0.85rem;
  font-weight: 500;
}

.checkbox-row {
  flex-direction: row !important;
  align-items: center;
  gap: 0.5rem !important;
}

.sticky-actions {
  position: sticky;
  bottom: 0;
  background: linear-gradient(transparent, var(--bg) 25%);
  padding-top: 1rem;
  margin-top: 0.5rem;
}

.search-mode-form {
  display: flex;
  flex-wrap: wrap;
  align-items: flex-end;
  gap: 1rem;
}

.search-mode-fieldset {
  border: 1px solid var(--border);
  border-radius: 8px;
  padding: 0.5rem 0.85rem;
  margin: 0;
}

.search-mode-fieldset legend {
  padding: 0 0.35rem;
}

.radio-inline {
  display: inline-flex;
  align-items: center;
  gap: 0.35rem;
  margin-right: 1rem;
  font-weight: 500;
  font-size: 0.9rem;
}

.search-field-grow {
  flex: 1;
  min-width: 220px;
  display: flex;
  flex-direction: column;
  gap: 0.35rem;
  font-weight: 600;
  font-size: 0.85rem;
}

.search-actions {
  display: flex;
  gap: 0.5rem;
}

.variant-table {
  font-size: 0.82rem;
}

.variant-table th {
  white-space: normal;
  max-width: 8rem;
}

.variant-table .cell-wrap {
  white-space: normal;
  word-break: break-word;
  max-width: 14rem;
}

.variant-table .cell-small {
  font-size: 0.78rem;
  max-width: 18rem;
}

.variant-table .cell-nowrap {
  white-space: nowrap;
}

.variant-table .cell-strong {
  font-weight: 600;
}

.form-card h3 {
  margin-top: 0;
}
/* Objective list */
.objective-list {
  margin: 0.75rem 0 0 1.25rem;
  display: flex;
  flex-direction: column;
  gap: 0.4rem;
}
.objective-list li {
  color: var(--text-muted, #6b7280);
  line-height: 1.6;
}

/* Team grid */
.team-grid {
  display: grid;
  grid-template-columns: repeat(auto-fill, minmax(260px, 1fr));
  gap: 1rem;
  margin-top: 0.75rem;
}
.team-card {
  display: flex;
  align-items: center;
  gap: 0.875rem;
  padding: 0.875rem;
  border: 1px solid var(--border, #e5e7eb);
  border-radius: 8px;
  background: var(--surface-alt, #f9fafb);
}
.team-avatar {
  width: 44px;
  height: 44px;
  border-radius: 50%;
  background: var(--primary, #2563eb);
  color: #fff;
  display: flex;
  align-items: center;
  justify-content: center;
  font-weight: 700;
  font-size: 1.1rem;
  flex-shrink: 0;
}
.team-info {
  display: flex;
  flex-direction: column;
  gap: 0.15rem;
}
.team-role {
  font-size: 0.8rem;
  color: var(--primary, #2563eb);
  font-weight: 500;
}

/* Contact form */
.contact-form {
  display: flex;
  flex-direction: column;
  gap: 1rem;
  margin-top: 0.75rem;
  max-width: 560px;
}
.form-row {
  display: flex;
  flex-direction: column;
  gap: 0.3rem;
}
.form-row label {
  font-size: 0.85rem;
  font-weight: 500;
}
.form-row input,
.form-row textarea {
  padding: 0.5rem 0.75rem;
  border: 1px solid var(--border, #e5e7eb);
  border-radius: 6px;
  font-size: 0.9rem;
  background: var(--surface, #fff);
  color: var(--text, #111);
  resize: vertical;
}
.form-row input:focus,
.form-row textarea:focus {
  outline: 2px solid var(--primary, #2563eb);
  outline-offset: 1px;
}
.contact-success {
  padding: 0.75rem 1rem;
  background: #ecfdf5;
  border: 1px solid #6ee7b7;
  border-radius: 6px;
  color: #065f46;
  margin-top: 0.5rem;
}
/* ── Lollipop variant map ─────────────────────────────────────────────── */
.lollipop-head {
  display: flex;
  flex-wrap: wrap;
  align-items: baseline;
  gap: 0.5rem 0.75rem;
  margin-bottom: 0.6rem;
}
.lollipop-head h3 {
  margin: 0;
}
.lollipop-gene {
  font-style: italic;
  color: var(--primary);
}
.lollipop-subtitle {
  font-size: 0.78rem;
  color: var(--muted);
  font-family: ui-monospace, SFMono-Regular, Menlo, monospace;
}
.lollipop-wrap {
  position: relative;
  width: 100%;
  overflow: hidden;
}
.lollipop-svg {
  width: 100%;
  height: auto;
  display: block;
  overflow: visible;
}
.lollipop-marker,
.lollipop-domain {
  cursor: pointer;
}
.lollipop-marker circle {
  transition: r 0.08s ease;
}
.lollipop-tick {
  fill: var(--muted);
  font-size: 12px;
}
.lollipop-axis-label {
  fill: var(--muted);
  font-size: 12.5px;
  font-weight: 600;
  letter-spacing: 0.02em;
}
.lollipop-domain-label {
  fill: #fff;
  font-size: 11px;
  font-weight: 600;
  pointer-events: none;
  paint-order: stroke;
}
.lollipop-count {
  fill: #fff;
  font-size: 10.5px;
  font-weight: 700;
  pointer-events: none;
}
.lollipop-label {
  fill: var(--muted);
  font-size: 11.5px;
  font-weight: 600;
  pointer-events: none;
  font-family: ui-monospace, SFMono-Regular, Menlo, monospace;
}
.lollipop-label-current {
  fill: var(--text);
  font-weight: 800;
}
.lollipop-legends {
  display: flex;
  flex-direction: column;
  gap: 0.4rem;
  margin-top: 0.85rem;
  padding-top: 0.7rem;
  border-top: 1px solid var(--border);
}
.lollipop-legend {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  gap: 0.3rem 1rem;
  font-size: 0.8rem;
  color: var(--text);
}
.lollipop-legend-title {
  font-size: 0.7rem;
  font-weight: 700;
  text-transform: uppercase;
  letter-spacing: 0.06em;
  color: var(--muted);
  min-width: 5.5rem;
}
.lollipop-legend-item {
  display: inline-flex;
  align-items: center;
  gap: 0.4rem;
}
.lollipop-swatch {
  display: inline-block;
  width: 11px;
  height: 11px;
  border-radius: 50%;
  border: 1px solid rgba(0, 0, 0, 0.25);
  flex: none;
}
.lollipop-swatch-sq {
  border-radius: 2px;
}
.lollipop-tooltip {
  position: absolute;
  z-index: 20;
  max-width: 260px;
  pointer-events: none;
  background: var(--surface);
  border: 1px solid var(--border);
  border-radius: 8px;
  box-shadow: var(--shadow);
  padding: 0.5rem 0.65rem;
  font-size: 0.8rem;
}
.lollipop-tooltip-title {
  display: flex;
  align-items: center;
  gap: 0.4rem;
  font-weight: 700;
  margin-bottom: 0.3rem;
}
.lollipop-tooltip-body .mono {
  font-family: ui-monospace, SFMono-Regular, Menlo, monospace;
  font-size: 0.78rem;
}

/* ── Inline notice banner (e.g. inactivity logout) ────────────────────── */
.notice {
  border-radius: var(--radius);
  padding: 0.7rem 0.9rem;
  font-size: 0.88rem;
  margin: 0 0 0.9rem;
  border: 1px solid var(--border);
}
.notice-info {
  background: #eef6f8;
  border-color: #bfe0e6;
  color: #0b4b54;
}

/* ── Sortable table headers + filter controls ─────────────────────────── */
.th-sort {
  display: inline-flex;
  align-items: center;
  gap: 0.15rem;
  background: none;
  border: none;
  padding: 0;
  margin: 0;
  font: inherit;
  font-weight: 700;
  color: inherit;
  cursor: pointer;
  white-space: nowrap;
}
.th-sort:hover {
  color: var(--primary);
}
.th-sort-active {
  color: var(--primary);
}
.th-caret {
  font-size: 0.7em;
  min-width: 0.8em;
}
.search-field-acmg {
  display: flex;
  flex-direction: column;
  gap: 0.25rem;
  font-size: 0.85rem;
  color: var(--muted);
}
.search-field-acmg select {
  padding: 0.4rem 0.5rem;
  border: 1px solid var(--border);
  border-radius: 8px;
  background: var(--surface);
  color: var(--text);
  font: inherit;
  min-width: 12rem;
}
/* ACMG badge sits comfortably inside a table cell */
.variant-table .vbadge {
  white-space: nowrap;
}

/* ── Circos genome plot ───────────────────────────────────────────────── */
.circos-head {
  display: flex;
  flex-wrap: wrap;
  align-items: baseline;
  gap: 0.4rem 0.75rem;
  margin-bottom: 0.5rem;
}
.circos-head h3 { margin: 0; }
.circos-subtitle {
  font-size: 0.8rem;
  color: var(--muted);
}
.circos-wrap {
  position: relative;
  width: 100%;
  max-width: 560px;
  margin: 0 auto;
}
.circos-svg {
  width: 100%;
  height: auto;
  display: block;
  overflow: visible;
}
.circos-chrom-label {
  fill: var(--text);
  font-size: 12px;
  font-weight: 600;
}
.circos-count {
  fill: #fff;
  font-size: 9.5px;
  font-weight: 700;
  pointer-events: none;
}
.circos-center-value {
  fill: var(--primary);
  font-size: 40px;
  font-weight: 800;
}
.circos-center-label {
  fill: var(--muted);
  font-size: 13px;
  letter-spacing: 0.03em;
}
.circos-marker { cursor: pointer; }
.circos-marker circle { transition: r 0.08s ease; }
.circos-marker:hover circle { stroke: var(--text); stroke-width: 1.5; }
.circos-legend {
  display: flex;
  flex-wrap: wrap;
  justify-content: center;
  gap: 0.35rem 1rem;
  margin-top: 0.75rem;
  padding-top: 0.7rem;
  border-top: 1px solid var(--border);
  font-size: 0.8rem;
}
.circos-legend-item { display: inline-flex; align-items: center; gap: 0.4rem; }
.circos-swatch {
  display: inline-block;
  width: 11px; height: 11px;
  border-radius: 50%;
  border: 1px solid rgba(0,0,0,0.2);
  flex: none;
}
.circos-tooltip {
  position: absolute;
  z-index: 20;
  max-width: 240px;
  pointer-events: none;
  background: var(--surface);
  border: 1px solid var(--border);
  border-radius: 8px;
  box-shadow: var(--shadow);
  padding: 0.5rem 0.65rem;
  font-size: 0.8rem;
}
.circos-tooltip-title {
  display: flex; align-items: center; gap: 0.4rem;
  font-weight: 700; margin-bottom: 0.3rem;
}
.circos-hint {
  margin-top: 0.3rem;
  font-size: 0.72rem;
  font-style: italic;
}

/* ── Ophthalmology department sections ─────────────────────────────────── */
.dept-grid {
  display: grid;
  grid-template-columns: repeat(auto-fill, minmax(290px, 1fr));
  gap: 1rem;
  margin-bottom: 1.25rem;
}
.dept-card {
  display: flex;
  gap: 0.85rem;
  align-items: flex-start;
  background: var(--surface);
  border: 1px solid var(--border);
  border-radius: var(--radius);
  padding: 1.05rem 1.1rem;
  box-shadow: var(--shadow);
  text-decoration: none;
  color: var(--text);
  transition: border-color 120ms ease, transform 120ms ease, box-shadow 120ms ease;
}
.dept-card:hover {
  border-color: var(--primary);
  transform: translateY(-2px);
  box-shadow: 0 12px 32px rgba(20, 35, 47, 0.12);
}
.dept-card-empty {
  opacity: 0.72;
}
.dept-icon {
  flex: none;
  width: 42px;
  height: 42px;
  display: grid;
  place-items: center;
  border-radius: 10px;
  background: linear-gradient(135deg, #e8f4f7 0%, #d5eaf0 100%);
  color: var(--primary);
}
.dept-icon svg {
  width: 24px;
  height: 24px;
}
.dept-body {
  display: flex;
  flex-direction: column;
  gap: 0.3rem;
  min-width: 0;
}
.dept-name {
  font-size: 1rem;
  line-height: 1.25;
}
.dept-desc {
  display: block;
}
.dept-counts {
  display: flex;
  flex-wrap: wrap;
  gap: 0.3rem 0.75rem;
  margin-top: 0.15rem;
  font-size: 0.78rem;
  color: var(--muted);
}
.dept-count b {
  color: var(--primary);
  font-weight: 700;
}
.dept-pending {
  font-style: italic;
}

/* Gene chips on a department page */
.gene-chip-list {
  display: flex;
  flex-wrap: wrap;
  gap: 0.4rem;
  margin-top: 0.6rem;
}
.gene-chip-link {
  text-decoration: none;
  transition: background 120ms ease, border-color 120ms ease;
}
.gene-chip-link:hover {
  border-color: var(--primary);
  background: #e8f4f7;
}
.gene-chip-count {
  display: inline-block;
  margin-left: 0.35rem;
  padding: 0 0.32rem;
  border-radius: 999px;
  background: var(--primary);
  color: #fff;
  font-size: 0.7rem;
  font-weight: 700;
  line-height: 1.5;
}
.gene-chip-empty {
  opacity: 0.55;
}
.gene-chip-empty .gene-chip-count {
  background: var(--muted);
}